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KMID : 0363420230370030017
Journal of Korean Oriental Pediatrics
2023 Volume.37 No. 3 p.17 ~ p.34
Herbal Medicine for Coronavirus Disease 2019 (COVID-19) in Children: a Literature Review
Lee Ji-Hong

Yang In-Jun
Abstract
Objectives : Few studies to date reviewed herbal medicines prescribed to pediatric patients with coronavirus disease 2019
(COVID-19). We aimed to summarize and analyze these herbal medicines.

Methods : Nine databases were searched for studies published up until November 24, 2020. Nine case reports and one case series involving 17 pediatric patients were included in the study. The clinical symptoms, interventions, outcomes,
pattern identification, composition, and frequency of herbal medicine administration were analyzed.

Results : The symptoms of pediatric patients with COVID-19 treated with herbal medicines were mild or moderate.
Herbal medicines have been used to alleviate symptoms, such as fever and cough. No adverse events were reported.
All of the patients who received herbal medicines were discharged from the hospital after symptomatic relief.
Pattern identification revealed that the lungs were the most affected organs. Epidemic toxins, wind, dampness, and
heat were the primary etiological factors. More pediatric patients with COVID-19 were prescribed a combination
of herbal and Western medicines than herbal medicines alone. The frequently used herbs include Glycyrrhizae Radix
et Rhizoma, Lonicerae Flos, Scutellariae Radix, Armeniacae Semen, Citri Reticulatae Pericarpium, and Astragali
Radix.

Conclusions : Our review can serve as a reference for the treatment of COVID-19 in children.
KEYWORD
Coronavirus disease 2019, COVID-19, children, herbal medicine, Korean medicine, review
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